GETTING STARTED

1. Set realistic expectations

   • As the patient titrates, they may not see immediate clinical improvements^2,3

   Explain importance of titrating to realize full benefits⁴

2. Prepare for common AEs

   • Review AEs (eg, cough, headache, and throat irritation) and why they may occur⁵
   • Give patients specific instructions to proactively manage any AEs that occur
   • Complete AE Management section on the Referral Form

   See AE Management Approaches

   Stress that they should not stop treatment without consulting you

3. Ensure patients understand the dosing plan

   • TYVASO DPI can be titrated by starting with 16 mcg (1 cartridge) 4x daily and increasing by 16 mcg every 1-2 weeks⁶
   • TYVASO can be titrated by starting with 3 breaths per treatment session and increasing by 3 breaths every 1-2 weeks²
   • There is no maximum labeled dose with TYVASO or TYVASO DPI^2,6
   • Once reaching their maintenance dose, the patient should maintain that dose with each treatment session^2,6

   SEE DOSING

   Emphasize the importance of completing all 4 daily treatment sessions

You can help patients understand what to expect by walking them through the Referral Form.