PAH is a rare but debilitating disease that progressively limits blood flow in the lungs.1,2
PAH is a rare but debilitating and progressive disease
It affects 15 to ~60 people per 1 million inhabitants in countries where studies have been conducted (~1000 new cases diagnosed each year in the United States).1,3,4
It’s more commonly diagnosed in women (70%-80% of cases) and in older patients (50-65 years old)1,5*
Patients with PAH may Unknowingly be at Risk for Disease Progression6,7
SOURCE: Adapted from Klinger JR. J Respir Dis. 2009.
*PAH is more frequently diagnosed in elderly patients in current registries, while the mean age of patients in the first US NIH registry was 36 years.1
CO=cardiac output; PAP=pulmonary artery pressure; PVR=pulmonary vascular resistance; RAP=right atrial pressure.
Patients may be asymptomatic until advanced vasculopathy is evident7